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ß-Lactam selectivity of multidrug transporters AcrB and AcrD resides in the proximal binding pocket.
Kobayashi, Naoki; Tamura, Norihisa; van Veen, Hendrik W; Yamaguchi, Akihito; Murakami, Satoshi.
Afiliação
  • Kobayashi N; Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan; Faculty of Pharmaceutical Science, Teikyo Heisei University, Nakano, Nakano-ku, Tokyo 164-8530, Japan; Graduate School of Pharmaceutical Sciences, Osaka University,
  • Tamura N; Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan; Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.
  • van Veen HW; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, United Kingdom.
  • Yamaguchi A; Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan; Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.
  • Murakami S; Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka 567-0047, Japan; Department of Life Science, Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama 226-8501, Japan. Electronic address: murakami@bio.titech.ac.jp.
J Biol Chem ; 289(15): 10680-10690, 2014 Apr 11.
Article em En | MEDLINE | ID: mdl-24558035
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Proteínas de Escherichia coli / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Farmacorresistência Bacteriana Múltipla / Beta-Lactamas / Escherichia coli Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Proteínas de Escherichia coli / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Farmacorresistência Bacteriana Múltipla / Beta-Lactamas / Escherichia coli Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2014 Tipo de documento: Article