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The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: study design, data analysis, interpretation.
Lebrec, Hervé; Molinier, Brigitte; Boverhof, Darrell; Collinge, Mark; Freebern, Wendy; Henson, Kristin; Mytych, Daniel T; Ochs, Hans D; Wange, Ronald; Yang, Yung; Zhou, Lei; Arrington, Joshua; Christin-Piché, Marie Soleil; Shenton, Jacintha.
Afiliação
  • Lebrec H; Amgen, Seattle, WA, USA. Electronic address: hlebrec@amgen.com.
  • Molinier B; Sanofi-Aventis R&D, Montpellier, France.
  • Boverhof D; The Dow Chemical Company, Midland, MI, USA.
  • Collinge M; Pfizer, Inc., Groton, CT, USA.
  • Freebern W; Bristol-Myers Squibb Company, New Brunswick, NJ, USA.
  • Henson K; Novartis Institutes for Biomedical Research Inc., East Hanover, NJ, USA.
  • Mytych DT; Amgen, Thousand Oaks, CA, USA.
  • Ochs HD; Department of Pediatrics, University of Washington, and Seattle Children's Research Institute, Seattle, WA, USA.
  • Wange R; Food and Drug Administration, Silver Spring, MD, USA.
  • Yang Y; Office of Pesticides Programs, US Environmental Protection Agency, Washington, DC, USA.
  • Zhou L; Amgen, Thousand Oaks, CA, USA.
  • Arrington J; Covance Inc., Madison, WI, USA.
  • Christin-Piché MS; Charles River Laboratories, Montreal, Canada.
  • Shenton J; MedImmune Ltd., Cambridge, UK.
Regul Toxicol Pharmacol ; 69(1): 7-21, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24566336
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bioensaio / Linfócitos T / Medição de Risco / Formação de Anticorpos Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bioensaio / Linfócitos T / Medição de Risco / Formação de Anticorpos Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article