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Ca2+-binding motif of ßγ-crystallins.
Srivastava, Shanti Swaroop; Mishra, Amita; Krishnan, Bal; Sharma, Yogendra.
Afiliação
  • Srivastava SS; Centre for Cellular and Molecular Biology (CCMB), Council of Scientific and Industrial Research (CSIR), Uppal Road, Hyderabad-500 007, India.
  • Mishra A; Centre for Cellular and Molecular Biology (CCMB), Council of Scientific and Industrial Research (CSIR), Uppal Road, Hyderabad-500 007, India.
  • Krishnan B; Centre for Cellular and Molecular Biology (CCMB), Council of Scientific and Industrial Research (CSIR), Uppal Road, Hyderabad-500 007, India.
  • Sharma Y; Centre for Cellular and Molecular Biology (CCMB), Council of Scientific and Industrial Research (CSIR), Uppal Road, Hyderabad-500 007, India. Electronic address: yogendra@ccmb.res.in.
J Biol Chem ; 289(16): 10958-10966, 2014 Apr 18.
Article em En | MEDLINE | ID: mdl-24567326
ßγ-Crystallin-type double clamp (N/D)(N/D)XX(S/T)S motif is an established but sparsely investigated motif for Ca(2+) binding. A ßγ-crystallin domain is formed of two Greek key motifs, accommodating two Ca(2+)-binding sites. ßγ-Crystallins make a separate class of Ca(2+)-binding proteins (CaBP), apparently a major group of CaBP in bacteria. Paralleling the diversity in ßγ-crystallin domains, these motifs also show great diversity, both in structure and in function. Although the expression of some of them has been associated with stress, virulence, and adhesion, the functional implications of Ca(2+) binding to ßγ-crystallins in mediating biological processes are yet to be elucidated.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Proteínas de Bactérias / Proteínas de Ligação ao Cálcio / Cálcio / Beta-Cristalinas / Gama-Cristalinas Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Proteínas de Bactérias / Proteínas de Ligação ao Cálcio / Cálcio / Beta-Cristalinas / Gama-Cristalinas Idioma: En Ano de publicação: 2014 Tipo de documento: Article