Recent studies of genetic dysfunction in pelvic organ prolapse: the role of collagen defects.
Aust N Z J Obstet Gynaecol
; 54(3): 198-205, 2014 Jun.
Article
em En
| MEDLINE
| ID: mdl-24575973
ABSTRACT
Gynaecologists are becoming increasingly aware that women with a family history of prolapse are at an increased risk of prolapse refractory to treatment. In the past five years, several genetic mutations have been shown to correlate with increased prolapse susceptibility. These mutations can result in disordered collagen metabolism, which weaken the fascial support of the pelvic organs. This review examines the contemporary evidence regarding the role of collagen in prolapse.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Colágeno
/
Prolapso de Órgão Pélvico
Tipo de estudo:
Systematic_reviews
Limite:
Female
/
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article