Toxic effects of extracellular histones and their neutralization by vitreous in retinal detachment.

Kawano, Hiroki; Ito, Takashi; Yamada, Shingo; Hashiguchi, Teruto; Maruyama, Ikuro; Hisatomi, Toshio; Nakamura, Makoto; Sakamoto, Taiji

Kawano, Hiroki; Ito, Takashi; Yamada, Shingo; Hashiguchi, Teruto; Maruyama, Ikuro; Hisatomi, Toshio; Nakamura, Makoto; Sakamoto, Taiji.

Afiliação

Kawano H; Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Ito T; Department of Systems Biology in Thromboregulation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Yamada S; Shino-Test Corporation, Kanagawa, Japan.
Hashiguchi T; Department of Laboratory and Vascular Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Maruyama I; Department of Systems Biology in Thromboregulation, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Hisatomi T; Department of Ophthalmology, Kyushu University, Fukuoka, Japan.
Nakamura M; Department of Ophthalmology, Kobe University, Kobe, Japan.
Sakamoto T; Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

Lab Invest ; 94(5): 569-85, 2014 May.

Article em En | MEDLINE | ID: mdl-24614198

Assuntos

Histonas/metabolismo; Ácido Hialurônico/fisiologia; Descolamento Retiniano/metabolismo; Corpo Vítreo/fisiologia; Animais; Estudos de Casos e Controles; Morte Celular; Linhagem Celular; Líquido Extracelular/metabolismo; Histonas/antagonistas & inibidores; Humanos; Interleucina-8/metabolismo; Sistema de Sinalização das MAP Quinases; Estresse Oxidativo; Ratos; Retina/metabolismo; Retina/patologia; Descolamento Retiniano/patologia; Receptor 4 Toll-Like/metabolismo; Corpo Vítreo/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpo Vítreo / Descolamento Retiniano / Histonas / Ácido Hialurônico Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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