Your browser doesn't support javascript.
loading
Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series.
Cox, Jason M; Chu, Hong D; Yang, Christine; Shen, Hong C; Wu, Zhicai; Balsells, Jaume; Crespo, Alejandro; Brown, Patricia; Zamlynny, Beata; Wiltsie, Judyann; Clemas, Joseph; Gibson, Jack; Contino, Lisa; Lisnock, JeanMarie; Zhou, Gaochao; Garcia-Calvo, Margarita; Bateman, Thomas; Xu, Ling; Tong, Xinchun; Crook, Martin; Sinclair, Peter.
Afiliação
  • Cox JM; Department of Discovery Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA. Electronic address: jason_cox@merck.com.
  • Chu HD; Department of Discovery Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Yang C; Department of Discovery Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Shen HC; Department of Discovery Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Wu Z; Department of Discovery Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Balsells J; Department of Process Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Crespo A; Department of Chemistry Modeling & Informatics, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA.
  • Brown P; Department of Cardiovascular Diseases, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Zamlynny B; Department of Cardiovascular Diseases, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Wiltsie J; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Clemas J; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Gibson J; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Contino L; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Lisnock J; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Zhou G; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Garcia-Calvo M; Department of In Vitro Pharmacology, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Bateman T; Department of Drug Metabolism, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Xu L; Department of Drug Metabolism, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Tong X; Department of Drug Metabolism, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Crook M; Department of Cardiovascular Diseases, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
  • Sinclair P; Department of Discovery Chemistry, Merck Research Laboratories, 2000 Galloping Hill Rd, Kenilworth, NJ 07033, USA.
Bioorg Med Chem Lett ; 24(7): 1681-4, 2014 Apr 01.
Article em En | MEDLINE | ID: mdl-24630411
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazóis / Receptores de Mineralocorticoides / Antagonistas de Receptores de Mineralocorticoides / Amidas / Compostos Heterocíclicos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxazóis / Receptores de Mineralocorticoides / Antagonistas de Receptores de Mineralocorticoides / Amidas / Compostos Heterocíclicos Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article