Lymphangiosarcoma of the scalp.
J Cutan Med Surg
; 18(2): 132-6, 2014.
Article
em En
| MEDLINE
| ID: mdl-24636440
ABSTRACT
BACKGROUND:
Lymphangiosarcoma is a rare, aggressive malignancy that originates from the endothelial cells lining lymphatic vessels and carries an extremely poor prognosis. Its clinical and histologic features are often indistinguishable from angiosarcoma.OBJECTIVE:
We sought to better characterize the clinical and histologic features of lymphangiosarcoma.METHODS:
Case report and review of the literature.RESULTS:
A number of immunohistochemical markers, including Von Willebrand factor, Ulex europaeus agglutinin 1, CD31, VEGFR-3, D2-40, Prox-1, can be used to help differentiate lymphatic from vascular tissue.CONCLUSIONS:
Recent characterization of several new biologic markers has allowed greater differentiation between these tumors and may provide new therapeutic targets for treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Couro Cabeludo
/
Linfangiossarcoma
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article