[Type 2 autoimmune polyendocrine syndromes (APS-2)]. / Les syndromes polyendocriniens autoimmuns de type 2 (APS-2).
Bull Acad Natl Med
; 197(1): 31-40; discussion 40-1, 2013 Jan.
Article
em Fr
| MEDLINE
| ID: mdl-24672978
ABSTRACT
Type 2 autoimmune polyendocrine syndromes (APS-2) are the most frequent disorders associating several organ-specific autoimmune diseases. Their high prevalence is due to the fact that the main manifestations of APS-2, such as thyroidal autoimmunity, type 1 diabetes, autoimmune gastric atrophy and vitiligo, are common diseases. APS-2 represents a clinical model that can serve to help unravel the mechanisms underlying autoimmunity. Diagnosis of APS-2 is a challenge for the clinician, especially in poorly symptomatic forms, and may require systematic screening based on measurement of autoantibodies and functional markers.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poliendocrinopatias Autoimunes
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Humans
Idioma:
Fr
Ano de publicação:
2013
Tipo de documento:
Article