A novel synthetic approach to the bicyclo[5.3.1]undecan-11-one framework of vinigrol.
Org Biomol Chem
; 12(22): 3562-6, 2014 Jun 14.
Article
em En
| MEDLINE
| ID: mdl-24676561
ABSTRACT
The first synthetic attempt commencing from an eight-membered ring to approach the [5.3.1] bicyclic core of vinigrol has demonstrated the feasibility of using the conformational bias of the cyclooctane-ring system to realize highly diastereoselective reactions. The synthetic potential of the newly disclosed access to in/out isomerism may stimulate broader interests.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Bicíclicos com Pontes
/
Química Orgânica
/
Diterpenos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article