The number of reduced alignments between two DNA sequences.
BMC Bioinformatics
; 15: 94, 2014 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-24684679
ABSTRACT
BACKGROUND:
In this study we consider DNA sequences as mathematical strings. Total and reduced alignments between two DNA sequences have been considered in the literature to measure their similarity. Results for explicit representations of some alignments have been already obtained.RESULTS:
We present exact, explicit and computable formulas for the number of different possible alignments between two DNA sequences and a new formula for a class of reduced alignments.CONCLUSIONS:
A unified approach for a wide class of alignments between two DNA sequences has been provided. The formula is computable and, if complemented by software development, will provide a deeper insight into the theory of sequence alignment and give rise to new comparison methods. AMS SUBJECT CLASSIFICATION Primary 92B05, 33C20, secondary 39A14, 65Q30.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Alinhamento de Sequência
/
Análise de Sequência de DNA
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article