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The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming.
Lu, Junjie; Li, Hu; Hu, Ming; Sasaki, Takayo; Baccei, Anna; Gilbert, David M; Liu, Jun S; Collins, James J; Lerou, Paul H.
Afiliação
  • Lu J; Department of Pediatric Newborn Medicine and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02115, USA.
  • Li H; Center for Individualized Medicine, Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.
  • Hu M; Department of Statistics, Harvard University, Cambridge, MA 02138, USA.
  • Sasaki T; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.
  • Baccei A; Department of Pediatric Newborn Medicine and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02115, USA.
  • Gilbert DM; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.
  • Liu JS; Department of Statistics, Harvard University, Cambridge, MA 02138, USA.
  • Collins JJ; Howard Hughes Medical Institute, Department of Biomedical Engineering and Center of Synthetic Biology, Boston University, Boston, MA 02215, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02115, USA.
  • Lerou PH; Department of Pediatric Newborn Medicine and Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02115, USA. Electronic address: plerou@partners.org.
Cell Rep ; 7(1): 70-8, 2014 Apr 10.
Article em En | MEDLINE | ID: mdl-24685138
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação do DNA / Reprogramação Celular / Células-Tronco Pluripotentes Induzidas / Variações do Número de Cópias de DNA Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Replicação do DNA / Reprogramação Celular / Células-Tronco Pluripotentes Induzidas / Variações do Número de Cópias de DNA Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article