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Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons.
Chen, Hong; Qian, Kun; Du, Zhongwei; Cao, Jingyuan; Petersen, Andrew; Liu, Huisheng; Blackbourn, Lisle W; Huang, CindyTzu-Ling; Errigo, Anthony; Yin, Yingnan; Lu, Jianfeng; Ayala, Melvin; Zhang, Su-Chun.
Afiliação
  • Chen H; Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Qian K; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Du Z; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Cao J; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Petersen A; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Liu H; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Blackbourn LW; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Huang CL; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Errigo A; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Yin Y; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Lu J; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Ayala M; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.
  • Zhang SC; Waisman Center, University of Wisconsin, Madison, WI 53705, USA; Department of Neuroscience and Department of Neurology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA. Electronic address: zhang@waisman.wisc.edu.
Cell Stem Cell ; 14(6): 796-809, 2014 Jun 05.
Article em En | MEDLINE | ID: mdl-24704493
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Proteínas Mutantes / Células-Tronco Pluripotentes Induzidas / Esclerose Lateral Amiotrófica / Modelos Biológicos / Neurônios Motores Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase / Proteínas Mutantes / Células-Tronco Pluripotentes Induzidas / Esclerose Lateral Amiotrófica / Modelos Biológicos / Neurônios Motores Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article