1-Deoxynojirimycin attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells.

E, Shuang; Kijima, Ryo; Honma, Taro; Yamamoto, Kazushi; Hatakeyama, Yu; Kitano, Yasuna; Kimura, Toshiyuki; Nakagawa, Kiyotaka; Miyazawa, Teruo; Tsuduki, Tsuyoshi

E, Shuang; Kijima, Ryo; Honma, Taro; Yamamoto, Kazushi; Hatakeyama, Yu; Kitano, Yasuna; Kimura, Toshiyuki; Nakagawa, Kiyotaka; Miyazawa, Teruo; Tsuduki, Tsuyoshi.

Afiliação

E S; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Kijima R; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Honma T; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Yamamoto K; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Hatakeyama Y; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Kitano Y; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Kimura T; NARO Agricultural Research Center, Tsukuba 305-8666, Japan.
Nakagawa K; Food and Biodynamic Chemistry Laboratory, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Miyazawa T; Food and Biodynamic Chemistry Laboratory, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan.
Tsuduki T; Laboratory of Food and Biomolecular Science, Graduate School of Agriculture, Tohoku University, Sendai 981-8555, Japan. Electronic address: tsuzukit@biochem.tohoku.ac.jp.

Exp Gerontol ; 55: 63-9, 2014 Jul.

Article em En | MEDLINE | ID: mdl-24709343

Assuntos

1-Desoxinojirimicina/farmacologia; Senescência Celular/efeitos dos fármacos; Glucose/antagonistas & inibidores; Células Endoteliais da Veia Umbilical Humana/efeitos dos fármacos; 1-Desoxinojirimicina/administração & dosagem; Adesão Celular/efeitos dos fármacos; Morte Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Células Cultivadas; Técnicas de Cocultura; Relação Dose-Resposta a Droga; Avaliação Pré-Clínica de Medicamentos/métodos; Glucose/administração & dosagem; Glucose/farmacologia; Células Endoteliais da Veia Umbilical Humana/metabolismo; Células Endoteliais da Veia Umbilical Humana/fisiologia; Humanos; Monócitos/efeitos dos fármacos; Monócitos/fisiologia; NF-kappa B/metabolismo; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

1-Deoxynojirimycin; DNJ; HUVEC; High glucose; Mulberry; Senescence

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Senescência Celular / 1-Desoxinojirimicina / Células Endoteliais da Veia Umbilical Humana / Glucose Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google