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Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents.
Zhao, Yanan; Armeanu, Emilian; DiVerniero, Richard; Lewis, Terri A; Dobson, Richard C; Kontoyiannis, Dimitrios P; Roilides, Emmanuel; Walsh, Thomas J; Perlin, David S.
Afiliação
  • Zhao Y; Public Health Research Institute Center, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA Exserohilum Meningitis Research Consortium, New York, New York, USA.
  • Armeanu E; SICC LLC, Evansville, Indiana, USA.
  • DiVerniero R; Premier Orthopaedic Associates, Mullica Hill, New Jersey, USA.
  • Lewis TA; Graduate Institute of Rehabilitation Counseling, National Changhua University of Education, Changhua, Taiwan, China.
  • Dobson RC; 2117 Buffalo Rd., Suite 124, Rochester, New York, USA.
  • Kontoyiannis DP; Exserohilum Meningitis Research Consortium, New York, New York, USA Department of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Roilides E; Exserohilum Meningitis Research Consortium, New York, New York, USA 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Hippokration General Hospital, Salonika, Greece.
  • Walsh TJ; Exserohilum Meningitis Research Consortium, New York, New York, USA Transplantation-Oncology Infectious Diseases Program, Department of Pediatrics, Microbiology & Immunology, Weill Cornell Medical Center, New York, New York, USA.
  • Perlin DS; Public Health Research Institute Center, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA Exserohilum Meningitis Research Consortium, New York, New York, USA perlinds@njms.rutgers.edu.
J Clin Microbiol ; 52(6): 2212-5, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24719442
ABSTRACT
Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / DNA Fúngico / Metilprednisolona / Contaminação de Medicamentos / Fungemia / Fungos Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / DNA Fúngico / Metilprednisolona / Contaminação de Medicamentos / Fungemia / Fungos Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article