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Systemic administration of a recombinant AAV1 vector encoding IGF-1 improves disease manifestations in SMA mice.
Tsai, Li-Kai; Chen, Chien-Lin; Ting, Chen-Hung; Lin-Chao, Sue; Hwu, Wuh-Liang; Dodge, James C; Passini, Marco A; Cheng, Seng H.
Afiliação
  • Tsai LK; Department of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address: milikai@ntuh.gov.tw.
  • Chen CL; Department of Neurology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
  • Ting CH; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
  • Lin-Chao S; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
  • Hwu WL; Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan.
  • Dodge JC; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
  • Passini MA; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
  • Cheng SH; Genzyme, a Sanofi Company, Framingham, Massachusetts, USA.
Mol Ther ; 22(8): 1450-1459, 2014 Aug.
Article em En | MEDLINE | ID: mdl-24814151
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like I / Atrofia Muscular Espinal / Terapia Genética / Vetores Genéticos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like I / Atrofia Muscular Espinal / Terapia Genética / Vetores Genéticos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article