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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.
Sabouri, Zahra; Schofield, Peter; Horikawa, Keisuke; Spierings, Emily; Kipling, David; Randall, Katrina L; Langley, David; Roome, Brendan; Vazquez-Lombardi, Rodrigo; Rouet, Romain; Hermes, Jana; Chan, Tyani D; Brink, Robert; Dunn-Walters, Deborah K; Christ, Daniel; Goodnow, Christopher C.
Afiliação
  • Sabouri Z; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;
  • Schofield P; Immunology Division, Garvan Institute of Medical Research and.
  • Horikawa K; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;
  • Spierings E; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;
  • Kipling D; Institute of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom; and.
  • Randall KL; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia;
  • Langley D; Immunology Division, Garvan Institute of Medical Research and.
  • Roome B; Immunology Division, Garvan Institute of Medical Research and.
  • Vazquez-Lombardi R; Immunology Division, Garvan Institute of Medical Research and.
  • Rouet R; Immunology Division, Garvan Institute of Medical Research and.
  • Hermes J; Immunology Division, Garvan Institute of Medical Research and.
  • Chan TD; Immunology Division, Garvan Institute of Medical Research andSt Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW 2010, Australia;
  • Brink R; Immunology Division, Garvan Institute of Medical Research andSt Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW 2010, Australia;
  • Dunn-Walters DK; Department of Immunobiology, King's College London School of Medicine, London SE1 9RT, United Kingdom.
  • Christ D; Immunology Division, Garvan Institute of Medical Research andSt Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW 2010, Australia; d.christ@garvan.org.au chris.goodnow@anu.edu.au.
  • Goodnow CC; Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia; d.christ@garvan.org.au chris.goodnow@anu.edu.au.
Proc Natl Acad Sci U S A ; 111(25): E2567-75, 2014 Jun 24.
Article em En | MEDLINE | ID: mdl-24821781
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Região Variável de Imunoglobulina / Linfócitos B / Anergia Clonal / Centro Germinativo / Hipermutação Somática de Imunoglobulina Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Região Variável de Imunoglobulina / Linfócitos B / Anergia Clonal / Centro Germinativo / Hipermutação Somática de Imunoglobulina Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article