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Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity.
Sun, Ning; Chan, Fung-Yi; Lu, Yu-Jing; Neves, Marco A C; Lui, Hok-Kiu; Wang, Yong; Chow, Ka-Yan; Chan, Kin-Fai; Yan, Siu-Cheong; Leung, Yun-Chung; Abagyan, Ruben; Chan, Tak-Hang; Wong, Kwok-Yin.
Afiliação
  • Sun N; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Chan FY; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China; Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of Am
  • Lu YJ; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China; School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, China.
  • Neves MA; Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America.
  • Lui HK; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Wang Y; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Chow KY; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Chan KF; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Yan SC; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Leung YC; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Abagyan R; Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America; Molsoft L.L.C, San Diego, California, United States of America.
  • Chan TH; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
  • Wong KY; Department of Applied Biology and Chemical Technology and the State Key Laboratory of Chirosciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
PLoS One ; 9(5): e97514, 2014.
Article em En | MEDLINE | ID: mdl-24824618
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Berberina / Modelos Moleculares / Proteínas do Citoesqueleto / Bactérias Gram-Positivas / Antibacterianos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Berberina / Modelos Moleculares / Proteínas do Citoesqueleto / Bactérias Gram-Positivas / Antibacterianos Idioma: En Ano de publicação: 2014 Tipo de documento: Article