CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.

Wang, Hailong; Li, Yongjiang; Truong, Lan N; Shi, Linda Z; Hwang, Patty Yi-Hwa; He, Jing; Do, Johnny; Cho, Michael Jeffrey; Li, Hongzhi; Negrete, Alejandro; Shiloach, Joseph; Berns, Michael W; Shen, Binghui; Chen, Longchuan; Wu, Xiaohua

Wang, Hailong; Li, Yongjiang; Truong, Lan N; Shi, Linda Z; Hwang, Patty Yi-Hwa; He, Jing; Do, Johnny; Cho, Michael Jeffrey; Li, Hongzhi; Negrete, Alejandro; Shiloach, Joseph; Berns, Michael W; Shen, Binghui; Chen, Longchuan; Wu, Xiaohua.

Afiliação

Wang H; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Li Y; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Truong LN; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Shi LZ; The Institute of Engineering in Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
Hwang PY; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
He J; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Do J; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Cho MJ; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
Li H; Department of Molecular Medicine, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Negrete A; Biotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Shiloach J; Biotechnology Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Berns MW; The Institute of Engineering in Medicine, University of California at San Diego, La Jolla, CA 92093, USA; Department of Biomedical Engineering, Beckman Laser Institute, University of California at Irvine, Irvine, CA 92612, USA.
Shen B; Department of Radiation Biology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Chen L; Department of Pathology, Veterans Affairs Medical Center, Long Beach, CA 90822, USA.
Wu X; Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: xiaohwu@scripps.edu.

Mol Cell ; 54(6): 1012-1021, 2014 Jun 19.

Article em En | MEDLINE | ID: mdl-24837675

Assuntos

Proteínas de Transporte/metabolismo; Sítios Frágeis do Cromossomo/genética; Quebras de DNA de Cadeia Dupla; Reparo do DNA/genética; Sequências Repetidas Invertidas/genética; Proteínas Nucleares/metabolismo; Hidrolases Anidrido Ácido; Elementos Alu/genética; Composição de Bases/genética; Proteínas de Transporte/genética; Proteínas de Ciclo Celular/genética; Linhagem Celular; Enzimas Reparadoras do DNA/genética; Proteínas de Ligação a DNA/genética; Endodesoxirribonucleases; Endonucleases/genética; Recombinação Homóloga/genética; Humanos; Proteína Homóloga a MRE11; Mitose/genética; Proteínas Nucleares/genética; Recombinação Genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Transporte / Sítios Frágeis do Cromossomo / Reparo do DNA / Quebras de DNA de Cadeia Dupla / Sequências Repetidas Invertidas Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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