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Novel zinc-binding site in the E2 domain regulates amyloid precursor-like protein 1 (APLP1) oligomerization.
Mayer, Magnus C; Kaden, Daniela; Schauenburg, Linda; Hancock, Mark A; Voigt, Philipp; Roeser, Dirk; Barucker, Christian; Than, Manuel E; Schaefer, Michael; Multhaup, Gerhard.
Afiliação
  • Mayer MC; From the Institut für Chemie und Biochemie, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany.
  • Kaden D; From the Institut für Chemie und Biochemie, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany.
  • Schauenburg L; From the Institut für Chemie und Biochemie, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany.
  • Hancock MA; the Department of Pharmacology and Therapeutics, McGill University Montreal, Montreal, Quebec H3G 1Y6, Canada.
  • Voigt P; the Molekulare Pharmakologie und Zellbiologie, Thielallee 67-73, Neurowissenschaftliches Forschungszentrum, Charité-Universitätsmedizin Berlin, 14195 Berlin, Germany.
  • Roeser D; the Leibniz Institute for Age Research, Protein Crystallography Group, Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany, and.
  • Barucker C; the Department of Pharmacology and Therapeutics, McGill University Montreal, Montreal, Quebec H3G 1Y6, Canada.
  • Than ME; the Leibniz Institute for Age Research, Protein Crystallography Group, Fritz Lipmann Institute, Beutenbergstrasse 11, 07745 Jena, Germany, and.
  • Schaefer M; the Rudolf-Boehm-Institut für Pharmakologie und Toxikologie, Medizinische Fakultät der Universität Leipzig, Härtelstrasse 16-18, 04107 Leipzig, Germany.
  • Multhaup G; From the Institut für Chemie und Biochemie, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany, the Department of Pharmacology and Therapeutics, McGill University Montreal, Montreal, Quebec H3G 1Y6, Canada, gerhard.multhaup@mcgill.ca.
J Biol Chem ; 289(27): 19019-30, 2014 Jul 04.
Article em En | MEDLINE | ID: mdl-24855651
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zinco / Precursor de Proteína beta-Amiloide / Multimerização Proteica Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zinco / Precursor de Proteína beta-Amiloide / Multimerização Proteica Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article