Involvement of glutamate-cystine/glutamate transporter system in aspirin-induced acute gastric mucosa injury.

Du, Jie; Li, Xiao-Hui; Zhang, Wang; Yang, Yong-Mei; Wu, Yue-Han; Li, Wen-Qun; Peng, Jun; Li, Yuan-Jian

Du, Jie; Li, Xiao-Hui; Zhang, Wang; Yang, Yong-Mei; Wu, Yue-Han; Li, Wen-Qun; Peng, Jun; Li, Yuan-Jian.

Afiliação

Du J; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Li XH; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Zhang W; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Yang YM; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Wu YH; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Li WQ; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Peng J; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
Li YJ; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China. Electronic address: yuan_jianli@sina.com.

Biochem Biophys Res Commun ; 450(1): 135-41, 2014 Jul 18.

Article em En | MEDLINE | ID: mdl-24866234

Assuntos

Sistema X-AG de Transporte de Aminoácidos/metabolismo; Sistema y+ de Transporte de Aminoácidos/metabolismo; Aspirina/administração & dosagem; Mucosa Gástrica/metabolismo; Ácido Glutâmico/metabolismo; Úlcera Gástrica/induzido quimicamente; Úlcera Gástrica/metabolismo; Animais; Anti-Inflamatórios não Esteroides; Linhagem Celular; Sobrevivência Celular/efeitos dos fármacos; Relação Dose-Resposta a Droga; Mucosa Gástrica/efeitos dos fármacos; Mucosa Gástrica/patologia; Humanos; Masculino; Ratos; Ratos Sprague-Dawley

Palavras-chave

Apoptosis; Aspirin; Gastric epithelial cells; Gastric mucosa injury; l-Glutamate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Úlcera Gástrica / Aspirina / Ácido Glutâmico / Sistema X-AG de Transporte de Aminoácidos / Sistema y/ de Transporte de Aminoácidos / Mucosa Gástrica Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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