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Pharmacokinetic and pharmacodynamic interactions between almorexant, a dual orexin receptor antagonist, and desipramine.
Cruz, Hans G; Hay, Justin L; Hoever, Petra; Alessi, Federica; te Beek, Erik T; van Gerven, Joop M A; Dingemanse, Jasper.
Afiliação
  • Cruz HG; Actelion Pharmaceuticals Ltd, Clinical Pharmacology, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.
  • Hay JL; Centre for Human Drug Research, Leiden, The Netherlands.
  • Hoever P; Actelion Pharmaceuticals Ltd, Clinical Pharmacology, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland.
  • Alessi F; Actelion Pharmaceuticals Ltd, Biostatistics, Allschwil, Switzerland.
  • te Beek ET; Centre for Human Drug Research, Leiden, The Netherlands.
  • van Gerven JM; Centre for Human Drug Research, Leiden, The Netherlands.
  • Dingemanse J; Actelion Pharmaceuticals Ltd, Clinical Pharmacology, Gewerbestrasse 16, CH-4123 Allschwil, Switzerland. Electronic address: jasper.dingemanse@actelion.com.
Eur Neuropsychopharmacol ; 24(8): 1257-68, 2014 Aug.
Article em En | MEDLINE | ID: mdl-24880753
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sangue / Citocromo P-450 CYP2D6 / Desipramina / Antagonistas dos Receptores de Orexina / Isoquinolinas / Acetamidas / Antidepressivos Tricíclicos Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sangue / Citocromo P-450 CYP2D6 / Desipramina / Antagonistas dos Receptores de Orexina / Isoquinolinas / Acetamidas / Antidepressivos Tricíclicos Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article