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Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells.
Felgentreff, Kerstin; Du, Likun; Weinacht, Katja G; Dobbs, Kerry; Bartish, Margarita; Giliani, Silvia; Schlaeger, Thorsten; DeVine, Alexander; Schambach, Axel; Woodbine, Lisa J; Davies, Graham; Baxi, Sachin N; van der Burg, Mirjam; Bleesing, Jack; Gennery, Andrew; Manis, John; Pan-Hammarström, Qiang; Notarangelo, Luigi D.
Afiliação
  • Felgentreff K; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115;
  • Du L; Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, SE 14186 Stockholm, Sweden;
  • Weinacht KG; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115;Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115;
  • Dobbs K; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115;
  • Bartish M; Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, SE 14186 Stockholm, Sweden;
  • Giliani S; A. Nocivelli Institute for Molecular Medicine, Pediatric Clinic, University of Brescia, Spedali Civili, 25123 Brescia, Italy;
  • Schlaeger T; Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115;
  • DeVine A; Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115;
  • Schambach A; Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115;Institute of Experimental Hematology, Hannover Medical School, D-30625 Hannover, Germany;
  • Woodbine LJ; Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9RQ, United Kingdom;
  • Davies G; Centre for Immunodeficiency, Great Ormond Street Hospital and Institute of Child Health, London WC1N 3JH, United Kingdom;
  • Baxi SN; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115;
  • van der Burg M; Department of Immunology, Erasmus Medical Center, 3015 GE, Rotterdam, The Netherlands;
  • Bleesing J; Division of Bone Marrow Transplant and Immunodeficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229;
  • Gennery A; Institute of Cellular Medicine, Pediatric Immunology, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne NE1 4LP, United Kingdom;
  • Manis J; Department of Transfusion Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115; and.
  • Pan-Hammarström Q; Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet at Karolinska University Hospital Huddinge, SE 14186 Stockholm, Sweden;
  • Notarangelo LD; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115;Harvard Stem Cell Institute, Cambridge, MA 02138 Luigi.Notarangelo@childrens.harvard.edu.
Proc Natl Acad Sci U S A ; 111(24): 8889-94, 2014 Jun 17.
Article em En | MEDLINE | ID: mdl-24889605
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quebras de DNA de Cadeia Dupla / Células-Tronco Pluripotentes Induzidas / Reparo do DNA por Junção de Extremidades Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quebras de DNA de Cadeia Dupla / Células-Tronco Pluripotentes Induzidas / Reparo do DNA por Junção de Extremidades Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article