Listen to Yourself: The Medial Prefrontal Cortex Modulates Auditory Alpha Power During Speech Preparation.
Cereb Cortex
; 25(11): 4029-37, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-24904068
ABSTRACT
How do we process stimuli that stem from the external world and stimuli that are self-generated? In the case of voice perception it has been shown that evoked activity elicited by self-generated sounds is suppressed compared with the same sounds played-back externally. We here wanted to reveal whether neural excitability of the auditory cortex-putatively reflected in local alpha band power--is modulated already prior to speech onset, and which brain regions may mediate such a top-down preparatory response. In the left auditory cortex we show that the typical alpha suppression found when participants prepare to listen disappears when participants expect a self-spoken sound. This suggests an inhibitory adjustment of auditory cortical activity already before sound onset. As a second main finding we demonstrate that the medial prefrontal cortex, a region known for self-referential processes, mediates these condition-specific alpha power modulations. This provides crucial insights into how higher-order regions prepare the auditory cortex for the processing of self-generated sounds. Furthermore, the mechanism outlined could provide further explanations to self-referential phenomena, such as "tickling yourself". Finally, it has implications for the so-far unsolved question of how auditory alpha power is mediated by higher-order regions in a more general sense.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Auditivo
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Percepção Auditiva
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Fonética
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Mapeamento Encefálico
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Potenciais Evocados
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article