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Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial.
Manns, Michael; Marcellin, Patrick; Poordad, Fred; de Araujo, Evaldo Stanislau Affonso; Buti, Maria; Horsmans, Yves; Janczewska, Ewa; Villamil, Federico; Scott, Jane; Peeters, Monika; Lenz, Oliver; Ouwerkerk-Mahadevan, Sivi; De La Rosa, Guy; Kalmeijer, Ronald; Sinha, Rekha; Beumont-Mauviel, Maria.
Afiliação
  • Manns M; Medizinische Hochschule Hannover, Department of Gastroenterology, Hepatology and Endocrinology, Hannover, Germany. Electronic address: manns.michael@mh-hannover.de.
  • Marcellin P; Service d'Hépatologie, Hôpital Beaujon, University Paris-Diderot and INSERM CRB3, Clichy, France.
  • Poordad F; Texas Liver Institute, University of Texas Health Science Center, San Antonio, TX, USA.
  • de Araujo ES; LIM-47 Hospital das Clinicas of the University of São Paulo School of Medicine, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
  • Buti M; Hospital Vall d'Hebron and Ciberhed del Instituto Carlos III, Barcelona, Spain.
  • Horsmans Y; Université Catholique de Louvain St Luc, Brussels, Belgium.
  • Janczewska E; ID Clinic, Myslowice, Poland.
  • Villamil F; CIPREC, Buenos Aires, Argentina.
  • Scott J; Janssen Global Services, High Wycombe, UK.
  • Peeters M; Janssen Infectious Diseases, Beerse, Belgium.
  • Lenz O; Janssen Infectious Diseases, Beerse, Belgium.
  • Ouwerkerk-Mahadevan S; Janssen Research and Development, Beerse, Belgium.
  • De La Rosa G; Janssen Global Services, Titusville, NJ, USA.
  • Kalmeijer R; Janssen Global Services, Titusville, NJ, USA.
  • Sinha R; Janssen Infectious Diseases, Beerse, Belgium.
  • Beumont-Mauviel M; Janssen Infectious Diseases, Beerse, Belgium.
Lancet ; 384(9941): 414-26, 2014 Aug 02.
Article em En | MEDLINE | ID: mdl-24907224
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Polietilenoglicóis / Ribavirina / Sulfonamidas / Interferon-alfa / Hepatite C Crônica / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Polietilenoglicóis / Ribavirina / Sulfonamidas / Interferon-alfa / Hepatite C Crônica / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article