Haloarchaeal gas vesicle nanoparticles displaying Salmonella SopB antigen reduce bacterial burden when administered with live attenuated bacteria.

DasSarma, Priya; Negi, Vidya Devi; Balakrishnan, Arjun; Karan, Ram; Barnes, Susan; Ekulona, Folasade; Chakravortty, Dipshikha; DasSarma, Shiladitya

DasSarma, Priya; Negi, Vidya Devi; Balakrishnan, Arjun; Karan, Ram; Barnes, Susan; Ekulona, Folasade; Chakravortty, Dipshikha; DasSarma, Shiladitya.

Afiliação

DasSarma P; Institute of Marine and Environmental Technology and Department of Microbiology and Immunology, University of Maryland, Baltimore, MD, USA.
Negi VD; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Balakrishnan A; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Karan R; Institute of Marine and Environmental Technology and Department of Microbiology and Immunology, University of Maryland, Baltimore, MD, USA.
Barnes S; Institute of Marine and Environmental Technology and Department of Microbiology and Immunology, University of Maryland, Baltimore, MD, USA.
Ekulona F; Institute of Marine and Environmental Technology and Department of Microbiology and Immunology, University of Maryland, Baltimore, MD, USA.
Chakravortty D; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India. Electronic address: dipa@mcbl.iisc.ernet.in.
DasSarma S; Institute of Marine and Environmental Technology and Department of Microbiology and Immunology, University of Maryland, Baltimore, MD, USA. Electronic address: sdassarma@som.umaryland.edu.

Vaccine ; 32(35): 4543-4549, 2014 Jul 31.

Article em En | MEDLINE | ID: mdl-24950351

Assuntos

Proteínas de Bactérias/imunologia; Portadores de Fármacos/administração & dosagem; Nanopartículas/administração & dosagem; Vacinas contra Salmonella/imunologia; Salmonella typhimurium/imunologia; Vesículas Secretórias/imunologia; Estruturas Animais/microbiologia; Animais; Carga Bacteriana; Proteínas de Bactérias/genética; Citocinas/metabolismo; Feminino; Halobacterium salinarum/genética; Halobacterium salinarum/metabolismo; Injeções Intraperitoneais; Leucócitos Mononucleares/imunologia; Masculino; Camundongos Endogâmicos BALB C; Salmonelose Animal/imunologia; Salmonelose Animal/prevenção & controle; Vacinas contra Salmonella/administração & dosagem; Vacinas contra Salmonella/genética; Vesículas Secretórias/genética

Palavras-chave

Antigen display; Enteric disease; Haloarchaea; Nanoparticle; Salmonella

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salmonella typhimurium / Proteínas de Bactérias / Portadores de Fármacos / Vesículas Secretórias / Vacinas contra Salmonella / Nanopartículas Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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