Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults.

Tchistiakova, Ekaterina; Anderson, Nicole D; Greenwood, Carol E; MacIntosh, Bradley J

Tchistiakova, Ekaterina; Anderson, Nicole D; Greenwood, Carol E; MacIntosh, Bradley J.

Afiliação

Tchistiakova E; Department of Medical Biophysics, University of Toronto, 610 University Ave., Toronto, ON M5G 2M9, Canada ; Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, 2075 Bayview Ave., Toronto, ON M4N 3M5, Canada ; Brain Sciences Research Program, Sunnybrook Research Institute, 2075 Bayv
Anderson ND; Department of Psychology, University of Toronto, 100 St. George Street, Toronto, ON M5S 1A8, Canada ; Rotman Research Institute, Baycrest, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada ; Department of Medicine (Psychiatry), University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Can
Greenwood CE; Rotman Research Institute, Baycrest, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada ; Department of Nutritional Sciences, University of Toronto, FitzGerald Building, 150 College Street, Toronto, ON M5S 3E2, Canada.
MacIntosh BJ; Department of Medical Biophysics, University of Toronto, 610 University Ave., Toronto, ON M5G 2M9, Canada ; Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, 2075 Bayview Ave., Toronto, ON M4N 3M5, Canada ; Brain Sciences Research Program, Sunnybrook Research Institute, 2075 Bayv

Neuroimage Clin ; 5: 36-41, 2014.

Article em En | MEDLINE | ID: mdl-24967157

Assuntos

Córtex Cerebral/patologia; Circulação Cerebrovascular/fisiologia; Diabetes Mellitus Tipo 2/patologia; Hipertensão/patologia; Idoso; Atrofia/patologia; Atrofia/fisiopatologia; Suspensão da Respiração; Córtex Cerebral/fisiopatologia; Diabetes Mellitus Tipo 2/complicações; Diabetes Mellitus Tipo 2/fisiopatologia; Feminino; Humanos; Hipertensão/complicações; Hipertensão/fisiopatologia; Imageamento por Ressonância Magnética; Masculino; Tamanho do Órgão/fisiologia

Palavras-chave

3DMPRAGE, three-dimensional magnetization-prepared rapid gradient-echo; BH, breath hold; BOLD, blood oxygenation level dependent imaging; CThk, cortical thickness; CVR, cerebrovascular reactivity; Cerebrovascular reactivity; Cortical thickness; Diabetes; FLAIR, fluid attenuation inversion recovery; FLEX, fuzzy lesion extractor; HBA1C, hemoglobin A1C; HTN, hypertension; Hypertension; T2DM, type 2 diabetes mellitus; TICS, Telephone Interview for Cognitive Status; WMH, white matter hyperintensities

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Circulação Cerebrovascular / Diabetes Mellitus Tipo 2 / Hipertensão Tipo de estudo: Risk_factors_studies Limite: Aged / Female / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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