SARA-Coffee web server, a tool for the computation of RNA sequence and structure multiple alignments.
Nucleic Acids Res
; 42(Web Server issue): W356-60, 2014 Jul.
Article
em En
| MEDLINE
| ID: mdl-24972831
ABSTRACT
This article introduces the SARA-Coffee web server; a service allowing the online computation of 3D structure based multiple RNA sequence alignments. The server makes it possible to combine sequences with and without known 3D structures. Given a set of sequences SARA-Coffee outputs a multiple sequence alignment along with a reliability index for every sequence, column and aligned residue. SARA-Coffee combines SARA, a pairwise structural RNA aligner with the R-Coffee multiple RNA aligner in a way that has been shown to improve alignment accuracy over most sequence aligners when enough structural data is available. The server can be accessed from http//tcoffee.crg.cat/apps/tcoffee/dosaracoffee.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
RNA
/
Alinhamento de Sequência
/
Análise de Sequência de RNA
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article