Injectable microbeads with a thermo-responsive shell and a pH-responsive core as a dual-switch-controlled release system.

ABSTRACT

Treating inflammation with a dual-switch-controlled release system The release of a drug from the developed microbead system occurs only in response to both an increase in local temperature and an acidic environmental pH. This dual-switch-controlled release system has the advantages of distinguishing between inflamed and healthy tissues to improve treatment efficacy.