Intravoxel incoherent motion MRI of the healthy pancreas: Monoexponential and biexponential apparent diffusion parameters of the normal head, body and tail.
J Magn Reson Imaging
; 41(5): 1236-41, 2015 May.
Article
em En
| MEDLINE
| ID: mdl-24979657
ABSTRACT
BACKGROUND:
To investigate the monoexponential and biexponential apparent diffusion parameters in different anatomical regions of the healthy pancreas using intravoxel incoherent motion (IVIM) diffusion weighted imaging (DWI).METHODS:
Fifty-seven healthy volunteers (age, 45.0 ± 10.8 years) were recruited. DWI of the pancreas was performed with 9 b-values (0, 20, 50, 100, 200, 400, 600, 800, and 1000 s/mm(2) , respectively). The ADC was calculated for all b-values using linear regression yielding ADCtotal . The ADCb value of the monoexponential DWI, slow component of diffusion (ADCslow ), incoherent microcirculation (ADCfast ) and perfusion fraction (f) of the biexponential DWI were calculated for the pancreas head, body and tail. Dependency of the parameters on the anatomical regions was analyzed using Friedman test.RESULTS:
All of the mean ADC400 , ADC600 , ADC800 , ADC1000 , ADCtotal and f values differed significantly among the anatomical regions with the lowest values were observed in the tail of pancreas (P < 0.05). The Friedman test results demonstrated a significant decline of the mean ADC values of the monoexponential DWI from b20 to b1000 for the three anatomical regions respectively (P < 0.001).CONCLUSION:
Multi-b-value DWI derived quantitative parameters including ADC400 , ADC600 , ADC800 , ADC1000 , ADCtotal , and f differed significantly among the pancreatic head, body and tail, with the lowest values obtained in the tail.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pâncreas
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Imageamento por Ressonância Magnética
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Interpretação de Imagem Assistida por Computador
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Artefatos
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Imageamento Tridimensional
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Técnicas de Imagem de Sincronização Respiratória
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article