Ultrastructure of cytoplasmic and nuclear inosine-5'-monophosphate dehydrogenase 2 "rods and rings" inclusions.

Juda, Pavel; Smigová, Jana; Kovácik, Lubomír; Bártová, Eva; Raska, Ivan

Juda, Pavel; Smigová, Jana; Kovácik, Lubomír; Bártová, Eva; Raska, Ivan.

Afiliação

Juda P; Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, Czech Republic (PJ, JS, LK, IR)Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Brno, Czech Republic (EB) pavel.juda@gmail.com.
Smigová J; Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, Czech Republic (PJ, JS, LK, IR)Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Brno, Czech Republic (EB).
Kovácik L; Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, Czech Republic (PJ, JS, LK, IR)Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Brno, Czech Republic (EB).
Bártová E; Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, Czech Republic (PJ, JS, LK, IR)Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Brno, Czech Republic (EB).
Raska I; Charles University in Prague, First Faculty of Medicine, Institute of Cellular Biology and Pathology, Czech Republic (PJ, JS, LK, IR)Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Brno, Czech Republic (EB).

J Histochem Cytochem ; 62(10): 739-50, 2014 Oct.

Article em En | MEDLINE | ID: mdl-24980853

Assuntos

Núcleo Celular/enzimologia; Núcleo Celular/ultraestrutura; Citoplasma/enzimologia; Citoplasma/ultraestrutura; IMP Desidrogenase/química; IMP Desidrogenase/ultraestrutura; Transporte Ativo do Núcleo Celular/efeitos dos fármacos; Núcleo Celular/metabolismo; Inibidores Enzimáticos/farmacologia; Células HeLa; Humanos; IMP Desidrogenase/antagonistas & inibidores; IMP Desidrogenase/metabolismo

Palavras-chave

Inosine-5'-monophosphate dehydrogenase; Rods and Rings; correlative light and electron microscopy; electron tomography; inclusions; inhibitors of IMPDH; ultrastructure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Celular / Citoplasma / IMP Desidrogenase Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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