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RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway.
Alonso-Curbelo, Direna; Riveiro-Falkenbach, Erica; Pérez-Guijarro, Eva; Cifdaloz, Metehan; Karras, Panagiotis; Osterloh, Lisa; Megías, Diego; Cañón, Estela; Calvo, Tonantzin G; Olmeda, David; Gómez-López, Gonzalo; Graña, Osvaldo; Sánchez-Arévalo Lobo, Víctor Javier; Pisano, David G; Wang, Hao-Wei; Ortiz-Romero, Pablo; Tormo, Damià; Hoek, Keith; Rodríguez-Peralto, José L; Joyce, Johanna A; Soengas, María S.
Afiliação
  • Alonso-Curbelo D; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Riveiro-Falkenbach E; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Pérez-Guijarro E; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Cifdaloz M; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Karras P; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Osterloh L; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Megías D; Confocal Microscopy Unit, Biotechnology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Cañón E; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Calvo TG; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Olmeda D; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Gómez-López G; Bioinformatics Unit, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Graña O; Bioinformatics Unit, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Sánchez-Arévalo Lobo VJ; Epithelial Carcinogenesis Laboratory, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Pisano DG; Bioinformatics Unit, Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Wang HW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Ortiz-Romero P; Instituto de Investigación i+12, Hospital 12 de Octubre, Universidad Complutense, Madrid 28041, Spain.
  • Tormo D; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.
  • Hoek K; Department of Dermatology, University Hospital of Zurich, Zurich 8091, Switzerland.
  • Rodríguez-Peralto JL; Instituto de Investigación i+12, Hospital 12 de Octubre, Universidad Complutense, Madrid 28041, Spain.
  • Joyce JA; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Soengas MS; Melanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain. Electronic address: msoengas@cnio.es.
Cancer Cell ; 26(1): 61-76, 2014 Jul 14.
Article em En | MEDLINE | ID: mdl-24981740
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Biomarcadores Tumorais / Linhagem da Célula / Proteínas rab de Ligação ao GTP / Lisossomos / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Biomarcadores Tumorais / Linhagem da Célula / Proteínas rab de Ligação ao GTP / Lisossomos / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article