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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.
Sleebs, Brad E; Lopaticki, Sash; Marapana, Danushka S; O'Neill, Matthew T; Rajasekaran, Pravin; Gazdik, Michelle; Günther, Svenja; Whitehead, Lachlan W; Lowes, Kym N; Barfod, Lea; Hviid, Lars; Shaw, Philip J; Hodder, Anthony N; Smith, Brian J; Cowman, Alan F; Boddey, Justin A.
Afiliação
  • Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Lopaticki S; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Marapana DS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • O'Neill MT; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Rajasekaran P; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Gazdik M; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Günther S; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
  • Whitehead LW; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Lowes KN; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Barfod L; University of Copenhagen and Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Hviid L; University of Copenhagen and Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
  • Shaw PJ; National Center for Genetic Engineering and Biotechnology (BIOTEC), Pathum Thani, Thailand.
  • Hodder AN; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Smith BJ; Department of Chemistry, La Trobe University, Victoria, Australia.
  • Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
  • Boddey JA; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia.
PLoS Biol ; 12(7): e1001897, 2014 Jul.
Article em En | MEDLINE | ID: mdl-24983235
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Sulfonamidas / Proteínas de Protozoários / Ácido Aspártico Endopeptidases / Ácido Aspártico Proteases Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Sulfonamidas / Proteínas de Protozoários / Ácido Aspártico Endopeptidases / Ácido Aspártico Proteases Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article