A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response.

Samuchiwal, Sachin Kumar; Tousif, Sultan; Singh, Dhiraj Kumar; Kumar, Arun; Ghosh, Anamika; Bhalla, Kuhulika; Prakash, Prem; Kumar, Sushil; Bhattacharyya, Maitree; Moodley, Prashini; Das, Gobardhan; Ranganathan, Anand

Samuchiwal, Sachin Kumar; Tousif, Sultan; Singh, Dhiraj Kumar; Kumar, Arun; Ghosh, Anamika; Bhalla, Kuhulika; Prakash, Prem; Kumar, Sushil; Bhattacharyya, Maitree; Moodley, Prashini; Das, Gobardhan; Ranganathan, Anand.

Afiliação

Das G; Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India. gobardhan.das07@gmail.com.

BMC Infect Dis ; 14: 355, 2014 Jul 01.

Article em En | MEDLINE | ID: mdl-24985537

Assuntos

Antígenos de Bactérias; Proteínas de Bactérias; Mycobacterium tuberculosis/imunologia; Tuberculose Pulmonar/microbiologia; Animais; Feminino; Humanos; Camundongos; Camundongos Endogâmicos BALB C; Mycobacterium tuberculosis/patogenicidade; Fragmentos de Peptídeos/farmacologia; Virulência

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Tuberculose Pulmonar / Mycobacterium tuberculosis / Antígenos de Bactérias Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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