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Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with κ agonist and µ agonist/antagonist activity.
Sun, Jian-Feng; Wang, Yu-Hua; Chai, Jing-Rui; Li, Fu-Ying; Hang, Ai; Lu, Gang; Tao, Yi-Min; Cheng, Yun; Chi, Zhi-Qiang; Neumeyer, John L; Zhang, Ao; Liu, Jing-Gen; Wang, Yu-Jun.
Afiliação
  • Sun JF; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China; Department of Physiology, Norman Bethune Medical College, Jilin University, Changchun 130021, China.
  • Wang YH; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210046, China.
  • Chai JR; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Li FY; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Hang A; Phamacology department, China Pharmaceutical University, Nanjing 211198, China.
  • Lu G; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Tao YM; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Cheng Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Chi ZQ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Neumeyer JL; Alcohol & Drug Abuse Research Center, McLean Hospital, Harvard Medical School, MA 02478, USA.
  • Zhang A; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China.
  • Liu JG; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China. Electronic address: jgliu@mail.shcnc.ac.cn.
  • Wang YJ; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China. Electronic address: yjwang@mail.simm.ac.cn.
Eur J Pharmacol ; 740: 455-63, 2014 Oct 05.
Article em En | MEDLINE | ID: mdl-24998879
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Opioides kappa / Receptores Opioides mu / Dependência de Heroína / Morfinanos / Antagonistas de Entorpecentes Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Opioides kappa / Receptores Opioides mu / Dependência de Heroína / Morfinanos / Antagonistas de Entorpecentes Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article