Galectin-1 accelerates wound healing by regulating the neuropilin-1/Smad3/NOX4 pathway and ROS production in myofibroblasts.

Lin, Yueh-Te; Chen, Jhih-Sian; Wu, Ming-Heng; Hsieh, I-Shan; Liang, Chen-Hsien; Hsu, Cheng-Lung; Hong, Tse-Ming; Chen, Yuh-Ling

Lin, Yueh-Te; Chen, Jhih-Sian; Wu, Ming-Heng; Hsieh, I-Shan; Liang, Chen-Hsien; Hsu, Cheng-Lung; Hong, Tse-Ming; Chen, Yuh-Ling.

Afiliação

Lin YT; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen JS; Institute of Oral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu MH; Institute for Translational Medicine, Taipei Medical University, Taipei, Taiwan.
Hsieh IS; Institute of Oral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Liang CH; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hsu CL; Department of Internal Medicine, Division of Hematology and Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Hong TM; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: tmhong@mail.ncku.edu.tw.
Chen YL; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Oral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: yuhling@mail.ncku.edu.tw.

J Invest Dermatol ; 135(1): 258-268, 2015 Jan.

Article em En | MEDLINE | ID: mdl-25007042

Assuntos

Fibroblastos/metabolismo; Galectina 1/metabolismo; NADPH Oxidases/metabolismo; Neuropilina-1/metabolismo; Proteína Smad3/metabolismo; Cicatrização/fisiologia; Animais; Movimento Celular/fisiologia; Proliferação de Células; Células Cultivadas; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Experimental/fisiopatologia; Modelos Animais de Doenças; Fibroblastos/citologia; Galectina 1/genética; Galectina 1/farmacologia; Gengiva/citologia; Células HEK293; Humanos; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; NADPH Oxidase 4; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/efeitos dos fármacos; Transdução de Sinais/fisiologia; Pele/lesões; Pele/metabolismo; Cicatrização/efeitos dos fármacos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cicatrização / NADPH Oxidases / Galectina 1 / Neuropilina-1 / Proteína Smad3 / Fibroblastos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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