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Regioselective hydroxylation of omeprazole enantiomers by bacterial CYP102A1 mutants.
Ryu, Sang Hoon; Park, Bo-Yeon; Kim, So-Young; Park, Sun-Ha; Jung, Hyun-Jin; Park, Min; Park, Ki Deok; Ahn, Taeho; Kang, Hyung-Sik; Yun, Chul-Ho.
Afiliação
  • Ryu SH; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Park BY; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Kim SY; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Park SH; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Jung HJ; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Park M; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Park KD; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Ahn T; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Kang HS; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
  • Yun CH; School of Biological Sciences and Technology (S.H.R., B.-Y.P., S.-Y.K, S.-H.P., H.-J.J., M.P., H.-S.K., C.-H.Y.), and Department of Biochemistry, College of Veterinary Medicine (T.A.), Chonnam National University, Gwangju, Republic of Korea; and Gwangju Center, Korea Basic Science Institute, Gwangju
Drug Metab Dispos ; 42(9): 1493-7, 2014 Sep.
Article em En | MEDLINE | ID: mdl-25008345
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Omeprazol / NADPH-Ferri-Hemoproteína Redutase / Sistema Enzimático do Citocromo P-450 / Hidroxilação Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Omeprazol / NADPH-Ferri-Hemoproteína Redutase / Sistema Enzimático do Citocromo P-450 / Hidroxilação Idioma: En Ano de publicação: 2014 Tipo de documento: Article