Synthesis of Indolyldiketopiperazines with NBS.

Ma, Yangmin; Ren, Decheng; Wu, Hao; Zhang, Jin; Feng, Tingting; Li, Yanchao

Ma, Yangmin; Ren, Decheng; Wu, Hao; Zhang, Jin; Feng, Tingting; Li, Yanchao.

Afiliação

Ma Y; Key Laboratory of Auxiliary Chemistry & Technology for Chemical Industry, Ministry of Education, Shaanxi University of Science & Technology, Xi'an, China.

Chirality ; 26(12): 790-2, 2014 Dec.

Article em En | MEDLINE | ID: mdl-25042109

ABSTRACT

ABSTRACT

Two series of indolyldiketopiperazines were synthesized starting from methyl 1-substituted-1,2,3,4-tetrahydro-ß-carboline-3-carboxylate hydrochlorides via N-bromo-succinimide (NBS) as an important reagent. All eight compounds were characterized by nuclear magnetic resonance (NMR) and elemental analysis. Furthermore, the mechanisms of NBS-reacted rearrangements are also discussed.

Assuntos

Bromosuccinimida/química; Piperazinas/química; Carbolinas/química; Ácidos Carboxílicos/química; Técnicas de Química Sintética; Estrutura Molecular; Piperazinas/síntese química

Palavras-chave

N-bromosuccinimide; conjugative effect; indolyldiketopiperazine; rearrangement

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Bromosuccinimida Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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