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The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.
Semenas, Julius; Hedblom, Andreas; Miftakhova, Regina R; Sarwar, Martuza; Larsson, Rikard; Shcherbina, Liliya; Johansson, Martin E; Härkönen, Pirkko; Sterner, Olov; Persson, Jenny L.
Afiliação
  • Semenas J; Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center.
  • Hedblom A; Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center.
  • Miftakhova RR; Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center.
  • Sarwar M; Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center.
  • Larsson R; Center for Analysis and Synthesis, Lund University, 22100, Lund, Sweden; and.
  • Shcherbina L; Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center, Division of Neuroendocrine Cell Biology, Department of Clinical Science, Clinical Research Center, and.
  • Johansson ME; Department of Laboratory Medicine, Lund University, 20502, Malmö, Sweden;
  • Härkönen P; Institute of Biomedicine, Department of Cell Biology and Anatomy, University of Turku, 20520 Turku, Finland.
  • Sterner O; Center for Analysis and Synthesis, Lund University, 22100, Lund, Sweden; and.
  • Persson JL; Division of Experimental Cancer Research, Department of Laboratory Medicine, Clinical Research Center, jenny_l.persson@med.lu.se.
Proc Natl Acad Sci U S A ; 111(35): E3689-98, 2014 Sep 02.
Article em En | MEDLINE | ID: mdl-25071204

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Fosfotransferases (Aceptor do Grupo Álcool) / Tetra-Hidroisoquinolinas / Dicetopiperazinas / Indóis / Isoquinolinas Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Fosfotransferases (Aceptor do Grupo Álcool) / Tetra-Hidroisoquinolinas / Dicetopiperazinas / Indóis / Isoquinolinas Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article