Towards the Development of Smart 3D "gated scaffolds" for on-command delivery.
Small
; 10(23): 4859-64, 2014 Dec 10.
Article
em En
| MEDLINE
| ID: mdl-25079146
ABSTRACT
A new approach towards the design of "gated scaffolds" based on the combination of capped mesoporous silica nanoparticles (MSNs) with porous biomaterials is reported. Using this approach, a 3D gelatin-based scaffold able to selectively deliver cargo in the presence of an APase enzyme is prepared and tested. This new design opens up the possibility of developing new smart biomaterials with advanced drug-delivery features.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Materiais Biocompatíveis
/
Portadores de Fármacos
/
Sistemas de Liberação de Medicamentos
/
Imageamento Tridimensional
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article