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High usage of topical fusidic acid and rapid clonal expansion of fusidic acid-resistant Staphylococcus aureus: a cautionary tale.
Williamson, Deborah A; Monecke, Stefan; Heffernan, Helen; Ritchie, Stephen R; Roberts, Sally A; Upton, Arlo; Thomas, Mark G; Fraser, John D.
Afiliação
  • Williamson DA; Department of Molecular Medicine and Pathology, University of Auckland Institute of Environmental Science and Research, Wellington Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
  • Monecke S; Alere Technologies, Jena Institute for Medical Microbiology and Hygiene, Dresden, Germany.
  • Heffernan H; Institute of Environmental Science and Research, Wellington.
  • Ritchie SR; Department of Molecular Medicine and Pathology, University of Auckland.
  • Roberts SA; Department of Clinical Microbiology, Auckland District Health Board.
  • Upton A; LabTests Auckland, New Zealand.
  • Thomas MG; Department of Molecular Medicine and Pathology, University of Auckland.
  • Fraser JD; Department of Molecular Medicine and Pathology, University of Auckland Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
Clin Infect Dis ; 59(10): 1451-4, 2014 Nov 15.
Article em En | MEDLINE | ID: mdl-25139961
ABSTRACT
Our aim was to assess national prescribing trends and determine longitudinal resistance patterns for topical antimicrobials in New Zealand. We observed a dramatic increase in fusidic acid (FA) resistance, and clonal expansion of FA-resistant Staphylococcus aureus. This increase was concurrent with a significant national increase in topical FA dispensing.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prescrições de Medicamentos / Infecções Estafilocócicas / Staphylococcus aureus / Farmacorresistência Bacteriana / Ácido Fusídico / Antibacterianos Limite: Humans País/Região como assunto: Oceania Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prescrições de Medicamentos / Infecções Estafilocócicas / Staphylococcus aureus / Farmacorresistência Bacteriana / Ácido Fusídico / Antibacterianos Limite: Humans País/Região como assunto: Oceania Idioma: En Ano de publicação: 2014 Tipo de documento: Article