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Influence of soy isoflavone on lindane cumulant in sprague-dawley rats.
Yang, Yang; Zhang, Yun Bo; Sheng, Wei; Fu, Zheng Hai; Wang, Zhe; Wang, Xiao; Guan, Si Yuan; Na, Xiao Lin.
Afiliação
  • Yang Y; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
  • Zhang YB; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
  • Sheng W; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
  • Fu ZH; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
  • Wang Z; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
  • Wang X; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
  • Guan SY; Department of Chemistry, Zhejiang University, Hangzhou 310058, Zhejiang, China.
  • Na XL; Department of Environmental Hygiene, Public Health College, Harbin Medical University, Harbin 150086, Heilongjiang, China.
Biomed Environ Sci ; 27(8): 637-40, 2014 Aug.
Article em En | MEDLINE | ID: mdl-25189611
ABSTRACT
Female Sprague-Dawley rats weighing 60-80 g were given different dosages of soy isoflavones and/or lindane for four weeks. Soy isoflavones was added in feed and lindane was given by oral gavage. We found that soy isoflavones could reduce the level of lindane in rat's serum and brain, but might cause the uterus hyperplasia. Lindane could inhibit the effect of soy isoflavones on uterus and significantly decrease the level of estradiol and testosterone in serum. This study indicated that soy isoflavones could reduce the level of lindane in rat's body. Lindane could reduce the level of hormones and decreased the effect of soy isoflavones on rat's uterus.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glycine max / Útero / Hexaclorocicloexano / Isoflavonas Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glycine max / Útero / Hexaclorocicloexano / Isoflavonas Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article