Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway.

Liu, G; Yu, F-X; Kim, Y C; Meng, Z; Naipauer, J; Looney, D J; Liu, X; Gutkind, J S; Mesri, E A; Guan, K-L

Liu, G; Yu, F-X; Kim, Y C; Meng, Z; Naipauer, J; Looney, D J; Liu, X; Gutkind, J S; Mesri, E A; Guan, K-L.

Afiliação

Liu G; 1] School of Life Sciences, Shandong University, Jinan, China [2] Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Yu FX; Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Kim YC; Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Meng Z; Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.
Naipauer J; Department of Microbiology and Immunology and Viral Oncology Program, Miami Center for AIDS Research, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Looney DJ; Department of Medicine, VA San Diego Healthcare System, The University of California, San Diego, La Jolla, CA, USA.
Liu X; School of Life Sciences, Shandong University, Jinan, China.
Gutkind JS; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
Mesri EA; Department of Microbiology and Immunology and Viral Oncology Program, Miami Center for AIDS Research, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Guan KL; Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.

Oncogene ; 34(27): 3536-46, 2015 Jul.

Article em En | MEDLINE | ID: mdl-25195862

Assuntos

Transformação Celular Viral/genética; Herpesvirus Humano 8/fisiologia; Proteínas Serina-Treonina Quinases/metabolismo; Aciltransferases; Animais; Proteínas de Ciclo Celular; Células Cultivadas; Regulação Neoplásica da Expressão Gênica; Células HEK293; Via de Sinalização Hippo; Humanos; Camundongos; Camundongos Nus; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Proteínas Serina-Treonina Quinases/genética; Sarcoma de Kaposi/genética; Sarcoma de Kaposi/metabolismo; Sarcoma de Kaposi/patologia; Transdução de Sinais/genética; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Viral / Proteínas Serina-Treonina Quinases / Herpesvirus Humano 8 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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