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Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice.
Peeraer, Eve; Bottelbergs, Astrid; Van Kolen, Kristof; Stancu, Ilie-Cosmin; Vasconcelos, Bruno; Mahieu, Michel; Duytschaever, Hilde; Ver Donck, Luc; Torremans, An; Sluydts, Ellen; Van Acker, Nathalie; Kemp, John A; Mercken, Marc; Brunden, Kurt R; Trojanowski, John Q; Dewachter, Ilse; Lee, Virginia M Y; Moechars, Diederik.
Afiliação
  • Peeraer E; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Bottelbergs A; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Van Kolen K; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Stancu IC; UCLouvain, Institute of Neuroscience, Group of Cellular and Molecular Neuroscience, B-1200 Woluwe-Saint-Lambert, Belgium.
  • Vasconcelos B; UCLouvain, Institute of Neuroscience, Group of Cellular and Molecular Neuroscience, B-1200 Woluwe-Saint-Lambert, Belgium.
  • Mahieu M; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Duytschaever H; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Ver Donck L; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Torremans A; Histogenex, B-2020 Antwerp, Belgium.
  • Sluydts E; Histogenex, B-2020 Antwerp, Belgium.
  • Van Acker N; Histogenex, B-2020 Antwerp, Belgium.
  • Kemp JA; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Mercken M; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Brunden KR; Center for Neurodegenerative Disease Research, Institute on Aging, Department of Pathology and Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
  • Trojanowski JQ; Center for Neurodegenerative Disease Research, Institute on Aging, Department of Pathology and Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
  • Dewachter I; UCLouvain, Institute of Neuroscience, Group of Cellular and Molecular Neuroscience, B-1200 Woluwe-Saint-Lambert, Belgium.
  • Lee VM; Center for Neurodegenerative Disease Research, Institute on Aging, Department of Pathology and Laboratory, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
  • Moechars D; Department of Neuroscience, Janssen Research and Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium. Electronic address: dmoechar@its.jnj.com.
Neurobiol Dis ; 73: 83-95, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25220759
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Tauopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Tauopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article