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Repeated oral dosing of TAS-102 confers high trifluridine incorporation into DNA and sustained antitumor activity in mouse models.
Tanaka, Nozomu; Sakamoto, Kazuki; Okabe, Hiroyuki; Fujioka, Akio; Yamamura, Keisuke; Nakagawa, Fumio; Nagase, Hideki; Yokogawa, Tatsushi; Oguchi, Kei; Ishida, Keiji; Osada, Akiko; Kazuno, Hiromi; Yamada, Yukari; Matsuo, Kenichi.
Afiliação
  • Tanaka N; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Sakamoto K; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Okabe H; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Fujioka A; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Yamamura K; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Nakagawa F; Taiho Pharmaceutical Co., Ltd., Tokushima Research Center, Ebisuno, Hiraishi, Kawauchi-cho, Tokushima 771-0194, Japan.
  • Nagase H; Taiho Pharmaceutical Co., Ltd., Tokushima Research Center, Ebisuno, Hiraishi, Kawauchi-cho, Tokushima 771-0194, Japan.
  • Yokogawa T; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Oguchi K; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Ishida K; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Osada A; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Kazuno H; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Yamada Y; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
  • Matsuo K; Taiho Pharmaceutical Co., Ltd., Tsukuba Research Center, Tsukuba, Ibaraki 300-2611, Japan.
Oncol Rep ; 32(6): 2319-26, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25230742
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Uracila / DNA de Neoplasias / Trifluridina / Neoplasias do Colo / Antineoplásicos Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Uracila / DNA de Neoplasias / Trifluridina / Neoplasias do Colo / Antineoplásicos Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article