Advances in molecular markers of germ cell cancer in patients with disorders of sex development.
Endocr Dev
; 27: 172-84, 2014.
Article
em En
| MEDLINE
| ID: mdl-25247654
ABSTRACT
The risk of malignant transformation of germ cells, leading to germ cell cancer (GCC) in patients with disorders of sex development, is highly heterogeneous and dependent on a number of parameters, of which the presence of Y-chromosomal material is essential. This chapter describes the networks, both protein-coding and regulatory processes, related to normal gonadal development and GCC, with focus on recent advances of molecular markers for early diagnosis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos do Desenvolvimento Sexual
/
Biomarcadores Tumorais
/
Neoplasias Embrionárias de Células Germinativas
Tipo de estudo:
Screening_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article