Rb suppresses human cone-precursor-derived retinoblastoma tumours.

Xu, Xiaoliang L; Singh, Hardeep P; Wang, Lu; Qi, Dong-Lai; Poulos, Bradford K; Abramson, David H; Jhanwar, Suresh C; Cobrinik, David

Xu, Xiaoliang L; Singh, Hardeep P; Wang, Lu; Qi, Dong-Lai; Poulos, Bradford K; Abramson, David H; Jhanwar, Suresh C; Cobrinik, David.

Afiliação

Xu XL; 1] Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA [2] Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.
Singh HP; 1] The Vision Center, Division of Ophthalmology, Department of Surgery, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA [2] The Saban Research Institute, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA.
Wang L; Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.
Qi DL; 1] The Vision Center, Division of Ophthalmology, Department of Surgery, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA [2] The Saban Research Institute, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA.
Poulos BK; Department of Pathology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA.
Abramson DH; Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.
Jhanwar SC; 1] Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA [2] Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA.
Cobrinik D; 1] The Vision Center, Division of Ophthalmology, Department of Surgery, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA [2] The Saban Research Institute, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Los Angeles, California 90027, USA [3] USC Eye

Nature ; 514(7522): 385-8, 2014 Oct 16.

Article em En | MEDLINE | ID: mdl-25252974

Assuntos

Células Fotorreceptoras Retinianas Cones/metabolismo; Células Fotorreceptoras Retinianas Cones/patologia; Proteína do Retinoblastoma/metabolismo; Retinoblastoma/metabolismo; Retinoblastoma/patologia; Transformação Celular Neoplásica; Fatores de Transcrição E2F/metabolismo; Regulação Neoplásica da Expressão Gênica; Genes do Retinoblastoma/genética; Xenoenxertos; Humanos; Proteína Proto-Oncogênica N-Myc; Proteínas Nucleares/metabolismo; Proteínas Oncogênicas/metabolismo; Especificidade de Órgãos; Proteínas Proto-Oncogênicas c-mdm2/metabolismo; Retinoblastoma/genética; Proteína do Retinoblastoma/deficiência; Proteína do Retinoblastoma/genética; Proteína p107 Retinoblastoma-Like/metabolismo; Proteína p130 Retinoblastoma-Like/deficiência; Proteína p130 Retinoblastoma-Like/metabolismo; Proteínas Quinases Associadas a Fase S/metabolismo; Células-Tronco/metabolismo; Células-Tronco/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retinoblastoma / Proteína do Retinoblastoma / Células Fotorreceptoras Retinianas Cones Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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