Prothrombin complex concentrate (Beriplex P/N)-related renal and cerebral infarctions in a patient with warfarin-associated intracerebral hemorrhage.

Lin, Shin-Yi; Tang, Sun-Chun; Shen, Li-Jiuan; Jeng, Jiann-Shing

Lin, Shin-Yi; Tang, Sun-Chun; Shen, Li-Jiuan; Jeng, Jiann-Shing.

Afiliação

Lin SY; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan.
Tang SC; Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: tangneuro@gmail.com.
Shen LJ; Department of Pharmacy, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Jeng JS; Stroke Center and Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan.

J Stroke Cerebrovasc Dis ; 24(1): e15-6, 2015 Jan.

Article em En | MEDLINE | ID: mdl-25282184

ABSTRACT

ABSTRACT

A 45-year-old man receiving warfarin treatment suffered from an intracerebral hemorrhage. Four-factor prothrombin complex concentrate (PCC) was administered to correct coagulopathy. However, bilateral renal infarcts and a cerebral infarct developed on day 5 and 7, respectively after PCC administration. Although the occurrence of PCC-related thromboembolism is low, health care practitioners should closely follow-up the symptoms and signs of thrombosis after PCC administration.

Assuntos

Anticoagulantes/efeitos adversos; Hemorragia Cerebral/induzido quimicamente; Infarto Cerebral/induzido quimicamente; Fator IX/efeitos adversos; Fator VII/efeitos adversos; Fator X/efeitos adversos; Infarto/induzido quimicamente; Rim/irrigação sanguínea; Protrombina/efeitos adversos; Varfarina/efeitos adversos; Anticoagulantes/uso terapêutico; Hemorragia Cerebral/tratamento farmacológico; Combinação de Medicamentos; Fator IX/uso terapêutico; Fator VII/uso terapêutico; Fator X/uso terapêutico; Humanos; Masculino; Pessoa de Meia-Idade; Protrombina/uso terapêutico; Varfarina/uso terapêutico

Palavras-chave

Prothrombin complex concentrate; renal infarct; stroke; thromboembolism; warfarin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Varfarina / Fator IX / Fator VII / Fator X / Protrombina / Hemorragia Cerebral / Infarto Cerebral / Infarto / Rim / Anticoagulantes Tipo de estudo: Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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