Synthesis, characterization, and X-ray attenuation properties of ultrasmall BiOI nanoparticles: toward renal clearable particulate CT contrast agents.
Inorg Chem
; 53(19): 10189-94, 2014 Oct 06.
Article
em En
| MEDLINE
| ID: mdl-25283335
ABSTRACT
A unique decelerated hydrolytic procedure is developed and reported here for the preparation of ultrasmall nanoparticles (NPs) of PVP-coated BiOI with a narrow size distribution, i.e., 2.8 ± 0.5 nm. The crystal structure of this compound is determined by X-ray powder diffraction using the bulk materials. The stability, cytotoxicity, and potential use of the PVP-coated ultrasmall BiOI NPs as a CT contrast agent are investigated. Because of the combined X-ray attenuation effect of bismuth and iodine, such NPs exhibit a CT value that is among the best of those of the inorganic nanoparticle-based CT contrast agents reported in the literature.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bismuto
/
Tomografia Computadorizada por Raios X
/
Meios de Contraste
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Nanopartículas
/
Iodetos
Limite:
Humans
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article