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Exendin-4 alleviates angiotensin II-induced senescence in vascular smooth muscle cells by inhibiting Rac1 activation via a cAMP/PKA-dependent pathway.
Zhao, Liang; Li, Ai Q; Zhou, Teng F; Zhang, Meng Q; Qin, Xiao M.
Afiliação
  • Zhao L; Institute of Cardiovascular Science, Peking University Health Science Center, Beijing, China; and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, China.
  • Li AQ; Institute of Cardiovascular Science, Peking University Health Science Center, Beijing, China; and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, China.
  • Zhou TF; Institute of Cardiovascular Science, Peking University Health Science Center, Beijing, China; and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, China.
  • Zhang MQ; Institute of Cardiovascular Science, Peking University Health Science Center, Beijing, China; and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, China.
  • Qin XM; Institute of Cardiovascular Science, Peking University Health Science Center, Beijing, China; and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing, China xmqin@bjmu.edu.cn.
Am J Physiol Cell Physiol ; 307(12): C1130-41, 2014 Dec 15.
Article em En | MEDLINE | ID: mdl-25298426
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Peçonhas / Angiotensina II / Sistemas do Segundo Mensageiro / Senescência Celular / Proteínas Quinases Dependentes de AMP Cíclico / AMP Cíclico / Proteínas rac1 de Ligação ao GTP / Miócitos de Músculo Liso / Hipoglicemiantes Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Peçonhas / Angiotensina II / Sistemas do Segundo Mensageiro / Senescência Celular / Proteínas Quinases Dependentes de AMP Cíclico / AMP Cíclico / Proteínas rac1 de Ligação ao GTP / Miócitos de Músculo Liso / Hipoglicemiantes Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article