First total synthesis of ganglioside DSG-A possessing neuritogenic activity.
Org Biomol Chem
; 12(46): 9345-9, 2014 Dec 14.
Article
em En
| MEDLINE
| ID: mdl-25338766
The first total synthesis of ganglioside DSG-A (1) is achieved via chemoselective glycosylation and a [1 + 1 + 2] synthetic strategy. We have also developed an efficient method that can be handled on large scale (50 g) for the synthesis of the phytosphingosine.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esfingosina
/
Gangliosídeos
Limite:
Animals
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article